Getting My ceesdekker.net To Work
Getting My ceesdekker.net To Work
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Employing one-molecule optical and AFM imaging and drive-spectroscopy methods, we look for to unravel the mechanistic aspects of the composition and dynamics of chromosomes. Our exploration passions incorporate:
You frequently get involved in conversations about science and faith. You've also written various textbooks on the topic. Don’t you are convinced at some point We're going to know every little thing and that God’s purpose are going to be about?
Back in 1991, Sumio Iijima of your NEC Company experienced reported the synthesis of carbon nanotubes. Band composition calculations suggested that these nanotubes could exhibit metallic band conduction. This could be a substantial gain about the conducting polymers we had explored, which were, in actual fact, disordered semiconductors featuring basically variable-array hopping conductivity.
Sculpting nano-electrodes that has a transmission electron beam for electrical and geometrical characterization of nanoparticles.
This yielded a breakthrough. Within only a few months, we were capable to evaluate transportation by means of somebody one-walled carbon nanotube. According to lower-temperature experiments by a superb PhD pupil in my team, Sander Tans (now a valued colleague and professor at Delft College of Technologies having an Energetic investigation lab at AMOLF in Amsterdam), we showed that carbon nanotubes have been legitimate quantum wires with quite long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic behaviour.
Experimental stage diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,
What distinguishes biology from chemistry is these factors collectively make up a living technique. The secret of explained lifestyle, I feel, lies within the interactions, the interplay of Those people molecules. The big issue regarding the origin of life remains to be unanswered. How did we at any time evolve from straightforward molecules in to the particularly sophisticated units we see these days? We don't know. I need to work on these kinds of significant, open inquiries.’
Studying DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
‘Yes, I fully grasp people were being stunned at https://www.ceesdekker.net some time. At the end of the nineties, Once i was in my forties, I was Professor of Molecular Electronics and I've to admit that it had turn into a little bit bored, I didn’t discover Substantially anymore. The field went extra into the applying side, how you may combine nanotubes into Digital circuits.
But carbon nanotubes have remained a analysis subject of appreciable interest to many. Without a doubt, the outlook on working with carbon nanotubes to build practical equipment, in spots including radio-frequency electronics, electronic electronics and flexible electronics, continues to be bright.
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Cees Dekker is Distinguished University Professor at TU Delft. Trained as a physicist, he pioneered nanotechnology with many discoveries on carbon nanotubes in the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His latest exploration focuses on (i) nanopores for protein sequencing; (ii) chromosome construction, particularly SMC motor protein; and (iii) building a dwelling artificial cell from lifeless molecules. Dekker is definitely an elected member of the KNAW and fellow into the APS plus the IOP.
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It had been an exceptionally fascinating time, for the duration of which I been given lots of assist from Delft College of Technology, exactly where I used to be a professor at enough time, And that i begun a number of collaborations with molecular biologists. That assisted me understand lots.’